Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with short life expectancy and no effective therapy.We previously identified upregulated miR-124 in NSC-34-motor neurons (MNs) expressing human SOD1-G93A (mSOD1) and established its implication in mSOD1 MN degeneration and glial cell activation.When anti-miR-124-treated mSOD1 MN (pr
Background & objectives: The main aim of this research is to provide literature on the Ocimum plant, and to know the significance of the Ocimum species carried out by pharmacognostic study and experimental design for GC-MS.Ocimum genus are very important for their therapeutic potential among the most important aromatic herbs.Methods: Extreme attent
Diversity in use of Question and Answering (Q/A) is evolving as a popular application in the area of Natural Language Processing (NLP).The alive unsupervised word embedding approaches are efficient to collect Latent-Semantic data on number of tasks.But certain methods are still unable to tackle issues such as polysemous-unaware with task-unaware ph
ERK pathway regulated the programmed death ligand-1 (PD-L1) expression which was linked to the response of programmed death-1 (PD-1)/PD-L1 blockade therapy.So it is tg02-0325m deducible that ERK inhibitor could enhance the efficacy of PD-1 inhibitor in cancer immunotherapy.In this study, PD0325901, an oral potent ERK inhibitor, strongly enhanced th
Abstract Classification of the Class Echinoidea is under significant revision in light of emerging molecular phylogenetic evidence.In particular, the sister-group relationships within the superorder Luminacea (Echinoidea: Irregularia) have been considerably updated.However, the placement of many families remains largely unresolved due to a series w